Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431822 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL8574988 | 0.89 | DYRK1A (0.50) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL8570704 | 0.86 | HDAC6 (0.58) | CYP1B1CYP1A1CYP1A2OPRD1HDAC6 | |
| SCHEMBL8429191 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL8429610 | 0.79 | DYRK1A (0.48) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL4575458 | 0.79 | KDM4E (0.47) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL8431065 | 0.78 | DYRK1A (0.55) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL8431081 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTCYP3A4MAPK1USP2 | |
| SCHEMBL8570785 | 0.76 | HDAC6 (0.56) | ALDH1A1CYP3A4KDM4EPOLBHPGD | |
| SCHEMBL10474033 | 0.75 | CYP1B1 (0.78) | ALDH1A1MAPTCYP3A4MAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803503-B1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR (FR) | 1999-11-03 | — | — | EP | disclosed |
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | disclosed |
| EP-0803503-A1 | Acids and esters of diosmetin and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-10-29 | — | — | EP | disclosed |