Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | PPP3CB | P16298 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429660 | 0.93 | CTSB (0.48) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL8251119 | 0.91 | CTSB (0.59) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL10171136 | 0.91 | CTSB (0.49) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL10171176 | 0.91 | CTSB (0.53) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL13523229 | 0.89 | CTSB (0.42) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL8427747 | 0.87 | CTSB (0.54) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL12670935 | 0.85 | CTSB (0.48) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL13707452 | 0.84 | CTSB (0.50) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL8429632 | 0.84 | CTSB (0.58) | CTSBPPP3CBCYP3A4 | |
| SCHEMBL8300968 | 0.84 | CTSB (0.60) | CTSBPPP3CBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229818-A1 | Hepatitis C inhibitor compound | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229818-A1 | Hepatitis C inhibitor compound | HAVCR2, GTF3C1, RNASE1 | CTSB 342/4885PPP3CB 467/4885CYP3A4 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.