Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | DNM2 | P50570 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1885381 | 0.79 | POLB (0.65) | TSHRKMT2AMEN1POLBAPOBEC3G | |
| SCHEMBL9413906 | 0.78 | TSHR (0.41) | TSHRKMT2AMEN1POLBHTT | |
| SCHEMBL1124026 | 0.78 | POLB (0.60) | TSHRKMT2AMEN1POLBHTT | |
| SCHEMBL9697628 | 0.77 | KMT2A (0.49) | TSHRKMT2AMEN1HTTTAAR1 | |
| SCHEMBL2757263 | 0.73 | KMT2A (0.61) | TSHRKMT2AMEN1POLBAPOBEC3G | |
| SCHEMBL27542100 | 0.72 | GAA (0.58) | TSHRKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL10516368 | 0.72 | TSHR (0.51) | TSHRKMT2AMEN1POLBAPOBEC3G | |
| SCHEMBL13780086 | 0.71 | MEN1 (0.59) | TSHRKMT2AMEN1THRBTAAR1 | |
| SCHEMBL5766295 | 0.71 | POLB (0.48) | TSHRKMT2AMEN1POLBAPOBEC3G | |
| SCHEMBL20635469 | 0.71 | HTT (0.53) | TSHRKMT2AHTTTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082587-A1 | 2,4,6-Triaminopyrimidines for the treatment of depression and/or anxiety | GALR3, GALR2, GALR1 | TSHR 105/4885KMT2A 2582/4885MEN1 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.