Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877961 | 0.78 | TSHR (0.42) | KMT2AHTTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL8429640 | 0.77 | TSHR (0.65) | KMT2AHTTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL9878842 | 0.77 | DHFR (0.54) | SMN1; SMN2MAPTTAAR1DHFRCYP1A2 | |
| SCHEMBL9594989 | 0.74 | TAAR1 (0.53) | KMT2AHTTMEN1TSHRSMN1; SMN2 | |
| SCHEMBL2130904 | 0.72 | DHFR (0.47) | KMT2AMEN1TSHRSMN1; SMN2LMNA | |
| SCHEMBL31098976 | 0.71 | DHFR (0.41) | HTTMAPTTAAR1DHFREGFR | |
| SCHEMBL1885381 | 0.70 | POLB (0.65) | KMT2AHTTMEN1TSHRLMNA | |
| SCHEMBL2409649 | 0.70 | TSHR (0.46) | KMT2AMEN1TSHRLMNADHFR | |
| SCHEMBL7526568 | 0.69 | ALDH1A1 (0.56) | KMT2AHTTMEN1MAPTLMNA | |
| SCHEMBL21765309 | 0.68 | SMN1; SMN2 (0.41) | KMT2AHTTTSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005158-A1 | 4-ANILINO-PYRIMIDINES, PROCESS FOR PRODUCING THE SAME, AGENTS CONTAINING THE SAME AND THEIR USE AS FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-02 | — | — | WO | disclosed |