Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL711997 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL28512738 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL7035160 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL2220986 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL124052 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL854170 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL21352472 | 0.97 | LMNA (0.53) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL21799190 | 0.97 | LMNA (0.53) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL6857287 | 0.94 | LMNA (0.50) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL6292053 | 0.94 | LMNA (0.50) | LMNAALDH1A1CA5ACA5BTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958001-A2 | METHOD FOR DESTROYING ENERGETIC MATERIALS | Commodore Applied Technologies, Inc. (US) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998028045-A2 | METHOD FOR DESTROYING ENERGETIC MATERIALS | COMMODORE APPLIED TECHNOLOGIES, INC. (US) | 1998-07-02 | — | — | WO | disclosed |