Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL711997 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL28512738 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL7035160 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL8430202 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL2220986 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL124052 | 1.00 | LMNA (0.56) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL21352472 | 0.97 | LMNA (0.53) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL21799190 | 0.97 | LMNA (0.53) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL6857287 | 0.94 | LMNA (0.50) | LMNAALDH1A1CA5ACA5BTHRB | |
| Glycerin SCHEMBL6292053 | 0.94 | LMNA (0.50) | LMNAALDH1A1CA5ACA5BTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236569-A1 | Lead-free Ballistic Modifier for Rocket Motor Propellants | USA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2025-07-24 | — | — | US | claimed |
| CN-117682929-A | Application of 3-bromo-5-fluoro-2, 4, 6-trinitroanisole in mixed explosive | 中北大学 | 2024-03-12 | — | — | CN | claimed |
| US-8778103-B2 | Energetic compositions including nitrate esters and articles including such energetic compositions | ALLIANT TECHSYSTEMS INC. (US) | 2014-07-15 | — | — | US | claimed |
| US-8658818-B2 | Methods of producing nitrate esters | ALLIANT TECHSYSTEMS INC. (US) | 2014-02-25 | — | — | US | claimed |
| US-20130055918-A1 | ENERGETIC COMPOSITIONS INCLUDING NITRATE ESTERS, METHODS OF FORMING SUCH ENERGETIC COMPOSITIONS, AND ARTICLES INCLUDING SUCH ENERGETIC COMPOSITIONS | ALLIANT TECHSYSTEMS INC. (US) | 2013-03-07 | — | — | US | claimed |
| US-20120237615-A1 | PHARMACEUTICAL COMPOSITIONS OF O-NITRO COMPOUNDS | RADIORX, INC., C/O INTERWEST VENTURE PARTNERS (US) | 2012-09-20 | — | — | US | claimed |
| US-20120130115-A1 | METHODS OF PRODUCING NITRATE ESTERS | ALLIANT TECHSYSTEMS INC. (US) | 2012-05-24 | — | — | US | claimed |
| US-20050133128-A1 | Method for making stable cured poly(glycidyl nitrate) | ALLIANT TECHSYSTEMS INC. | 2005-06-23 | — | — | US | claimed |
| US-20030089435-A1 | Method of synthesizing diglycerol tetranitrate, and solid rocket motor propellant containing the same | ORBITAL ATK, INC. | 2003-05-15 | — | — | US | claimed |
| US-6350871-B1 | Crystallization of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,903,11]-dodecane | ALLIANT TECHSYSTEMS INC. | 2002-02-26 | — | — | US | claimed |
| EP-1136468-A2 | Method of synthesizing diglycerol tetranitrate, and solid rocket motor propellant containing the same | Cordant Technologies, Inc. (US) | 2001-09-26 | — | — | EP | claimed |
| US-20250236569-A1 | Lead-free Ballistic Modifier for Rocket Motor Propellants | USA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2025-07-24 | — | — | US | disclosed |
| CN-117682929-A | Application of 3-bromo-5-fluoro-2, 4, 6-trinitroanisole in mixed explosive | 中北大学 | 2024-03-12 | — | — | CN | disclosed |
| US-9133150-B2 | O-nitro compounds and pharmaceutical compositions including same | ORBITAL ATK, INC. (US) | 2015-09-15 | — | — | US | disclosed |
| US-8778103-B2 | Energetic compositions including nitrate esters and articles including such energetic compositions | ALLIANT TECHSYSTEMS INC. (US) | 2014-07-15 | — | — | US | disclosed |
| EP-1136468-A3 | Method of synthesizing diglycerol tetranitrate, and solid rocket motor propellant containing the same | Cordant Technologies, Inc. (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-1136468-A3 | Method of synthesizing diglycerol tetranitrate, and solid rocket motor propellant containing the same | Cordant Technologies, Inc. (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-1136468-A2 | Method of synthesizing diglycerol tetranitrate, and solid rocket motor propellant containing the same | Cordant Technologies, Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-1136468-A2 | Method of synthesizing diglycerol tetranitrate, and solid rocket motor propellant containing the same | Cordant Technologies, Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-1136468-A2 | Method of synthesizing diglycerol tetranitrate, and solid rocket motor propellant containing the same | Cordant Technologies, Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130115-A1 | METHODS OF PRODUCING NITRATE ESTERS | TST, GMNN, TTN | LMNA 2648/4885ALDH1A1 954/4885CA5A 2162/4885 |
| US-20120237615-A1 | PHARMACEUTICAL COMPOSITIONS OF O-NITRO COMPOUNDS | NOS1, NOS2, NOS3 | LMNA 1625/4885ALDH1A1 1059/4885CA5A 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.