SCHEMBL8430211

SCHEMBL8430211

C=Cc1ccc(CNC(=O)CCl)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TPSAB1 Q15661 4/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 6/20 0.44
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TGM2 P21980 1/20 0.44
MAPT P10636 2/20 0.43
RAB9A P51151 2/20 0.42
POLB P06746 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
LMNA P02545 2/20 0.41
HPGD P15428 1/20 0.41
NPC1 O15118 1/20 0.41
GAA P10253 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
PRSS1 P07477 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9151730 0.87 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TGM2MAPTRAB9A
SCHEMBL26418343 0.83 MEN1 (0.59) TPSAB1ALDH1A1MEN1KMT2ALMNA
SCHEMBL13864006 0.83 TPSAB1 (0.44) TPSAB1ALDH1A1TGM2POLBLMNA
SCHEMBL13112977 0.83 TPSAB1 (0.49) TPSAB1ALDH1A1HTTTGM2RAB9A
SCHEMBL23565249 0.81 TPSAB1 (0.47) TPSAB1ALDH1A1TGM2RAB9AMEN1
SCHEMBL13101225 0.81 TPSAB1 (0.47) TPSAB1ALDH1A1HTTTGM2RAB9A
SCHEMBL14341628 0.80 CYP2D6 (0.50) TPSAB1ALDH1A1SMN1; SMN2TGM2MAPT
SCHEMBL14732584 0.80 CYP3A4 (0.56) TPSAB1ALDH1A1MEN1KMT2ALMNA
SCHEMBL9798143 0.80 ALDH1A1 (0.58) TPSAB1MAPK1ALDH1A1HTTSMN1; SMN2
SCHEMBL24242093 0.79 HSD17B10 (0.51) ALDH1A1SMN1; SMN2MAPTPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5429931-A Oxidized NAD, alcohol dehydrogenase, acrylic copolymer EASTMAN KODAK COMPANY (US) 1995-07-04 US claimed
EP-0419652-B1 POLYMERIC ELECTROPHORESIS MEDIA EASTMAN KODAK CO (US) 1994-01-05 EP claimed
EP-0626580-B1 Multilayer analytical element containing niacinamide and method for the determination of ethanol JOHNSON & JOHNSON CLIN DIAG (US) 1999-11-03 EP disclosed
EP-0476102-B1 CONTROL OF PRESSURE-FOG WITH GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED SOFT POLYMER LATEX PARTICLES EASTMAN KODAK CO (US) 1998-07-22 EP disclosed
EP-0478735-B1 USE OF GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED POLYMER PARTICLES FOR RELIEF FROM PRESSURE SENSITIVITY OF PHOTOGRAPHIC PRODUCTS EASTMAN KODAK CO (US) 1997-10-08 EP disclosed
EP-0572977-B1 Bilirubin assay using crosslinkable polymers JOHNSON & JOHNSON CLIN DIAG (US) 1997-08-13 EP disclosed
EP-0337785-B2 Diagnostic kit and method for rapid detection of antibodies JOHNSON & JOHNSON CLIN DIAG (US) 1996-03-13 EP disclosed
US-5429932-A Colorimetric analysis of ethanol EASTMAN KODAK COMPANY (US) 1995-07-04 US disclosed
US-5429931-A Oxidized NAD, alcohol dehydrogenase, acrylic copolymer EASTMAN KODAK COMPANY (US) 1995-07-04 US disclosed
US-5391483-A Using mixture of periodic acid and chromium trioxide EASTMAN KODAK COMPANY (US) 1995-02-21 US disclosed
EP-0468584-B1 Copolymers containing polyoxyalkylene side chains EASTMAN KODAK CO (US) 1995-01-18 EP disclosed
US-5055379-A Mixture of dye loaded polymeric particles covered with gelatin and bonded to a radiation-sensitive dichromate EASTMAN KODAK COMPANY (US) 1991-10-08 US disclosed
WO-1991014968-A1 CONTROL OF PRESSURE-FOG WITH GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED SOFT POLYMER LATEX PARTICLES EASTMAN KODAK COMPANY (US) 1991-10-03 WO disclosed
WO-1991014967-A1 USE OF GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED POLYMER PARTICLES FOR RELIEF FROM PRESSURE SENSITIVITY OF PHOTOGRAPHIC PRODUCTS EASTMAN KODAK COMPANY (US) 1991-10-03 WO disclosed
US-5026632-A Stress absorbing filler EASTMAN KODAK COMPANY (US) 1991-06-25 US disclosed
US-4948480-A DISSOLVING ACRYLAMIDE COPOLYMER IN WATER, ADDING BUFFER, ADDING CROSSLINKING AGENT FROM SEPARATE PACKAGE EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed
EP-0347137-A2 Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-12-20 EP disclosed
EP-0340653-A2 Kit for electrophoresis gel medium EASTMAN KODAK COMPANY (US) 1989-11-08 EP disclosed
WO-1989009939-A1 COMPOSITIONS, DIAGNOSTIC KIT AND METHOD FOR RAPID DETECTION OF ANTIBODIES EASTMAN KODAK COMPANY (US) 1989-10-19 WO disclosed
EP-0337785-A1 Diagnostic kit and method for rapid detection of antibodies Johnson & Johnson Clinical Diagnostics, Inc. (US) 1989-10-18 EP disclosed