SCHEMBL8430216

SCHEMBL8430216

C1=CC2=NC(c3ccccc3)=CC2=CC1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27843710 0.76 LMNA (0.36) PPARA
SCHEMBL6688803 0.71 PPARA (0.31) PPARA
SCHEMBL31468700 0.71 MAOA (0.41)
SCHEMBL7642819 0.71 PPARA (0.40) PPARA
SCHEMBL10772455 0.68
SCHEMBL11786643 0.68
SCHEMBL9983564 0.67
SCHEMBL9461527 0.67 PPARA (0.31) PPARA
SCHEMBL21151429 0.66 SMN1; SMN2 (0.44)
Hydrochloric Acid SCHEMBL3662296 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5910590-A INTERACTS WITH GABA BINDING SITE (THE BENZODIAZEPINE RECEPTOR); TREATMENT OF ANXIETY, SEIZURE AND SLEEP DISORDERS, ENHANCES ALERTNESS AND TREATMENT OF BENZODIAZEPINE OVERDOSES NEUROGEN CORPORATION (US) 1999-06-08 US disclosed