Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PGD | P52209 | 3/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349503 | 0.87 | TDP1 (0.42) | SMN1; SMN2SLC22A6TSHRTDP1PGD | |
| SCHEMBL30293 | 0.79 | TDP1 (0.48) | SMN1; SMN2SLC22A6TSHRTDP1GABRR1 | |
| SCHEMBL11389211 | 0.79 | MMP1 (0.47) | SMN1; SMN2SLC22A6TDP1PGDMMP1 | |
| SCHEMBL9573234 | 0.79 | TDP1 (0.52) | SMN1; SMN2SLC22A6TDP1MMP1MMP2 | |
| SCHEMBL1707892 | 0.78 | TDP1 (0.50) | SMN1; SMN2SLC22A6TSHRTDP1PGD | |
| SCHEMBL9406869 | 0.77 | TDP1 (0.46) | SMN1; SMN2SLC22A6TSHRTDP1GABRR1 | |
| SCHEMBL9406499 | 0.77 | TDP1 (0.46) | SMN1; SMN2SLC22A6TSHRTDP1GABRR1 | |
| SCHEMBL8558212 | 0.77 | TDP1 (0.46) | SMN1; SMN2SLC22A6TSHRTDP1GABRR1 | |
| SCHEMBL9053647 | 0.77 | TDP1 (0.46) | SMN1; SMN2SLC22A6TSHRTDP1GABRR1 | |
| Ammonia Solution, Strong SCHEMBL28156292 | 0.77 | TDP1 (0.52) | SMN1; SMN2SLC22A6TSHRTDP1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355809-B1 | PROCESS FOR PREPARING ETHER-CARBOXYLIC ACIDS AND SALTS | MONSANTO COMPANY (US) | 1993-04-14 | — | — | EP | claimed |
| US-5183473-A | Aqueous solution containing sulfatase which hydrolyzes stable, water soluble peroxydisulfate to provide peroxymonosulfate ions; for low temperature removal of blood stains from textiles | MONSANTO COMPANY (US) | 1993-02-02 | — | — | US | claimed |
| US-5028723-A | Calcium Ion Catalyzed Reaction In Alkaline Medium Of A Maleic Acid And Tartaric Acid Salt | MONSANTO COMPANY (US) | 1991-07-02 | — | — | US | claimed |
| US-4959496-A | REACTION OF MALEIC ACID SALTS WITH HYDORXY CARBOXYLIC ACIDS TO YIELD ETHER CARBOXYLATES | MONSANTO COMPANY (US) | 1990-09-25 | — | — | US | claimed |
| US-4950787-A | REACTING MALEIC ACID AND TARTARIC ACID SALTS IN THE PRESENCE OF CALCIUM CATALYST TO PRODUCE 1-HYDROXY-3-OXA-1,2,4,5-PENTANE TETRACARBOXYLIC ACID AND 3,6-DIOXA-1,2,4,5,7,8-OCTANE-HEXACARBOXYLIC ACID | MONSANTO COMPANY (US) | 1990-08-21 | — | — | US | claimed |
| EP-0364697-A1 | Process for preparing ether-carboxylic acids and salts | MONSANTO COMPANY (US) | 1990-04-25 | — | — | EP | claimed |
| EP-0356901-A1 | Process for preparing mixtures of ether-carboxylic acids and salts | MONSANTO COMPANY (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0355807-A2 | Process for the manufacture of ether carboxylic acids | MONSANTO COMPANY (US) | 1990-02-28 | — | — | EP | claimed |
| EP-0355809-A1 | Process for preparing ether-carboxylic acids and salts | MONSANTO COMPANY (US) | 1990-02-28 | — | — | EP | claimed |
| EP-0355806-A2 | Process for the manufacture of mixtures of ether carboxylic acids | MONSANTO COMPANY (US) | 1990-02-28 | — | — | EP | claimed |
| US-4904824-A | Chemical process | HORNG LIOU LIANG (US) | 1990-02-27 | — | — | US | claimed |
| US-4867901-A | CALCIUM CATALYST | CPFILMS INC. | 1989-09-19 | — | — | US | claimed |
| EP-0266723-A1 | Process for the preparation of 1-hydroxy-3-oxapentane-1,2,4,5-tetracarboxylic acid, of 3,6-dioxa-octane-1,2,4,5,7,8-hexacarboxylic acid, of their salts and their mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-11 | — | — | EP | claimed |
| JP-2117640-A | — | — | None | — | — | JP | disclosed |
| JP-11302691-A | — | — | None | — | — | JP | disclosed |
| JP-63130554-A | — | — | None | — | — | JP | disclosed |
| JP-S63130554-A | MANUFACTURE OF 1-HYDROXY-3-OXAPENTANE-1,2,4,5- TETRACARBOXYLIC ACID AND 3,6-DIOXAOCTANE- 1,2,4,5,7,8-HEXACARBOXYLIC ACID, SALTS THEREOF AND MIXTURE | HOECHST AG | 1988-06-02 | — | — | JP | disclosed |
| EP-0266723-A1 | Process for the preparation of 1-hydroxy-3-oxapentane-1,2,4,5-tetracarboxylic acid, of 3,6-dioxa-octane-1,2,4,5,7,8-hexacarboxylic acid, of their salts and their mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-11 | — | — | EP | disclosed |
| EP-0266723-A1 | Process for the preparation of 1-hydroxy-3-oxapentane-1,2,4,5-tetracarboxylic acid, of 3,6-dioxa-octane-1,2,4,5,7,8-hexacarboxylic acid, of their salts and their mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-11 | — | — | EP | disclosed |
| EP-0266723-A1 | Process for the preparation of 1-hydroxy-3-oxapentane-1,2,4,5-tetracarboxylic acid, of 3,6-dioxa-octane-1,2,4,5,7,8-hexacarboxylic acid, of their salts and their mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-05-11 | — | — | EP | disclosed |