Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597212 | 0.84 | PDPK1 (0.49) | CES2CES1GRM8GRM4KIF11 | |
| Cadaverine Tartrate SCHEMBL10560377 | 0.83 | PDE2A (0.50) | CES2CES1GRM8GRM4KIF11 | |
| SCHEMBL11902072 | 0.79 | GRM8 (0.50) | CES2CES1GRM8GRM4KIF11 | |
| SCHEMBL5225725 | 0.79 | GRM8 (0.50) | CES2CES1GRM8GRM4KIF11 | |
| SCHEMBL8426162 | 0.79 | HDAC3 (0.41) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL18125936 | 0.79 | GRM8 (0.50) | CES2CES1GRM8GRM4KIF11 | |
| SCHEMBL5018968 | 0.79 | NR1I2 (0.53) | CES2CES1GRM8GRM4KIF11 | |
| SCHEMBL4967991 | 0.79 | NR1I2 (0.53) | CES2CES1GRM8GRM4KIF11 | |
| SCHEMBL15137434 | 0.78 | KIF11 (0.46) | CES2CES1KIF11ACP3 | |
| SCHEMBL15670412 | 0.78 | KIF11 (0.46) | CES2CES1KIF11ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939561-A | Process for the preparation of β-phenylisoserine and β-lactam and their analogues | RHONE-POULENCE RORER S.A. (FR) | 1999-08-17 | — | — | US | disclosed |
| US-5763628-A | Process for the preparation of β-phenylisoserine and its analogues | RHONE-POULENCE RORER S.A. (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5608102-A | Process for the preparation of β-phenylisoserine and its analogues | RHONE-POULENC RORER S.A. (FR) | 1997-03-04 | — | — | US | disclosed |