Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512389 | 0.82 | GRM8 (0.45) | SLC1A3SLC1A2SLC1A1KDM4EBLM | |
| SCHEMBL9261826 | 0.82 | CYP2C9 (0.51) | HDAC4HDAC7HDAC5GRIK1SLC1A3 | |
| SCHEMBL8058962 | 0.81 | DPP4 (0.56) | KDM4ELMNAMAPK1HIF1A | |
| SCHEMBL939042 | 0.81 | DPP4 (0.56) | KDM4ELMNAMAPK1HIF1A | |
| SCHEMBL487425 | 0.81 | DPP4 (0.56) | KDM4ELMNAMAPK1HIF1A | |
| SCHEMBL4073511 | 0.81 | DPP4 (0.56) | KDM4ELMNAMAPK1HIF1A | |
| SCHEMBL5860807 | 0.81 | DPP4 (0.56) | KDM4ELMNAMAPK1HIF1A | |
| SCHEMBL939043 | 0.81 | DPP4 (0.56) | KDM4ELMNAMAPK1HIF1A | |
| SCHEMBL9257685 | 0.80 | LMNA (0.43) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7618552 | 0.80 | TPMT (0.40) | KDM4EBLMPMP22LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939561-A | Process for the preparation of β-phenylisoserine and β-lactam and their analogues | RHONE-POULENCE RORER S.A. (FR) | 1999-08-17 | — | — | US | disclosed |
| US-5763628-A | Process for the preparation of β-phenylisoserine and its analogues | RHONE-POULENCE RORER S.A. (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5608102-A | Process for the preparation of β-phenylisoserine and its analogues | RHONE-POULENC RORER S.A. (FR) | 1997-03-04 | — | — | US | disclosed |
| US-5476954-A | Condensing hydroxyl protected taxane derivative with oxazolidine derivative, decyclizing in acid medium, reacting butoxycarbonyl or benzoyl radical with amine, deprotecting, isolating, purifying product | RHONE-POULENC RORER S.A. (FR) | 1995-12-19 | — | — | US | disclosed |