SCHEMBL8430409

SCHEMBL8430409

CC(=O)O[C@H]1C(=O)N[C@@H]1c1cncs1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8428349 1.00 POLB (0.34) POLBMEN1ALDH1A1KMT2A
SCHEMBL7458769 0.78 ALDH1A1 (0.46) POLBMEN1ALDH1A1KMT2A
SCHEMBL7458765 0.78 ALDH1A1 (0.46) POLBMEN1ALDH1A1KMT2A
SCHEMBL8314886 0.78 ALDH1A1 (0.46) POLBMEN1ALDH1A1KMT2A
SCHEMBL8426374 0.71 POLB (0.31) POLB
SCHEMBL2112154 0.68 POLB (0.46) POLBMEN1ALDH1A1KMT2A
SCHEMBL2112157 0.68 POLB (0.46) POLBMEN1ALDH1A1KMT2A
SCHEMBL2112155 0.68 POLB (0.46) POLBMEN1ALDH1A1KMT2A
SCHEMBL5516078 0.68 POLB (0.46) POLBMEN1ALDH1A1KMT2A
SCHEMBL8489494 0.67 MAPT (0.41) POLBMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5939561-A Process for the preparation of β-phenylisoserine and β-lactam and their analogues RHONE-POULENCE RORER S.A. (FR) 1999-08-17 US disclosed