Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.67 |
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | PTGES | O14684 | 1/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658049 | 0.92 | PTGS2 (0.66) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL29103950 | 0.91 | PTGS2 (0.61) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL6458883 | 0.91 | PTGS2 (0.65) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL11832986 | 0.89 | PTGS2 (0.63) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL11553568 | 0.87 | PTGS2 (0.65) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL10651280 | 0.86 | PTGS2 (0.59) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL11570998 | 0.85 | PTGS2 (0.58) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL28817659 | 0.85 | PTGS2 (0.64) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL11621747 | 0.85 | PTGS2 (0.64) | PTGS2PTGS1AKR1C3AKR1C2PPARG | |
| SCHEMBL10654480 | 0.84 | PTGS2 (0.57) | PTGS2PTGS1AKR1C3AKR1C2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932245-A | Gelatin or collagen hydrolysate containing drug formulation that provides for immediate release of nanoparticle drug compounds | ALFATEC PHARMA GMBH (DE) | 1999-08-03 | — | — | US | disclosed |