Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432449 | 0.94 | LTB4R (0.54) | LTB4RMRGPRX4PTGER1TERT | |
| SCHEMBL8432889 | 0.92 | LTB4R (0.57) | LTB4RPTGER1TERTKDM4E | |
| SCHEMBL8434257 | 0.91 | LTB4R (0.58) | LTB4R | |
| SCHEMBL8434474 | 0.88 | LTB4R (0.56) | LTB4RPTGER1TERT | |
| SCHEMBL8430702 | 0.88 | LTB4R (0.51) | LTB4RMRGPRX4PTGER1TERT | |
| SCHEMBL8430532 | 0.87 | LTB4R (0.53) | LTB4RMRGPRX4TERTL3MBTL1 | |
| SCHEMBL8434178 | 0.87 | LTB4R (0.43) | LTB4RTERT | |
| SCHEMBL8434056 | 0.86 | LTB4R (0.51) | LTB4RMRGPRX4PTGER1 | |
| SCHEMBL8434513 | 0.86 | LTB4R (0.53) | LTB4RPTGER1 | |
| SCHEMBL8430615 | 0.85 | LTB4R (0.60) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929096-A | TREATING DISEASES ATTRIBUTING THEIR ORIGIN OR AFFECT TO LEUKOTRIENES, ANTIALLERGENS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |