Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432889 | 0.94 | LTB4R (0.57) | LTB4RPTGER1TERTCYP1A2CYP3A4 | |
| SCHEMBL8434140 | 0.89 | LTB4R (0.47) | LTB4RPTGER1TERTMAPT | |
| SCHEMBL8430563 | 0.88 | LTB4R (0.55) | LTB4RPTGER1TERTMRGPRX4 | |
| SCHEMBL8434056 | 0.88 | LTB4R (0.51) | LTB4RPTGER1MRGPRX4MAPT | |
| SCHEMBL8434513 | 0.88 | LTB4R (0.53) | LTB4RPTGER1 | |
| SCHEMBL8432449 | 0.86 | LTB4R (0.54) | LTB4RPTGER1TERTMRGPRX4 | |
| SCHEMBL8430495 | 0.84 | LTB4R (0.55) | LTB4RPTGER1TERTMRGPRX4CYP1A2 | |
| SCHEMBL8430541 | 0.84 | LTB4R (0.42) | LTB4RPTGER1 | |
| SCHEMBL8434257 | 0.83 | LTB4R (0.58) | LTB4R | |
| SCHEMBL8434474 | 0.81 | LTB4R (0.56) | LTB4RPTGER1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929096-A | TREATING DISEASES ATTRIBUTING THEIR ORIGIN OR AFFECT TO LEUKOTRIENES, ANTIALLERGENS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |