Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GPX4 | P36969 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27009973 | 0.82 | TRPM8 (0.51) | TRPM8KMT2AMEN1ALDH1A1GABRA1 | |
| SCHEMBL3521407 | 0.81 | TRPM8 (0.50) | TRPM8KMT2AMEN1ALDH1A1GABRA1 | |
| SCHEMBL11872443 | 0.75 | SMN1; SMN2 (0.45) | TRPM8ALDH1A1GABRA1GABRB2LMNA | |
| SCHEMBL10653725 | 0.73 | TRPM8 (0.45) | TRPM8KMT2AMEN1ALDH1A1GABRA1 | |
| SCHEMBL3523911 | 0.72 | TSHR (0.49) | TRPM8KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8426915 | 0.72 | ALDH1A1 (0.49) | TRPM8KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL20266539 | 0.72 | TRPM8 (0.44) | TRPM8KMT2AALDH1A1GABRA1GABRB2 | |
| SCHEMBL15624544 | 0.72 | TAAR1 (0.52) | KMT2AMEN1ALDH1A1HPGDGAA | |
| SCHEMBL24315703 | 0.72 | TAAR1 (0.46) | TRPM8GABRA1GABRB2L3MBTL1HPGD | |
| SCHEMBL14518799 | 0.72 | NPC1 (0.46) | TRPM8KMT2AMEN1ALDH1A1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859007-A | TREATMENT OF DIABETES, OBESITY | GLAXO WELLCOME INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0755384-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028391-A1 | CCK OR GASTRIN MODULATING 1,5 BENZODIAZEPINES DERIVATIVES | GLAXO WELLCOME INC. (US) | 1995-10-26 | — | — | WO | disclosed |