Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244463 | 0.91 | MAPT (0.58) | HSPA5KEAP1MAPTMEN1KMT2A | |
| SCHEMBL50932 | 0.91 | MAPT (0.58) | HSPA5KEAP1MAPTMEN1KMT2A | |
| SCHEMBL2513625 | 0.87 | HSPA5 (0.45) | HSPA5KEAP1MAPTMEN1KMT2A | |
| SCHEMBL7759834 | 0.86 | KEAP1 (0.48) | HSPA5KEAP1MAPTMEN1KMT2A | |
| SCHEMBL2512174 | 0.83 | CETP (0.49) | HSPA5MAPTMEN1KMT2ALMNA | |
| SCHEMBL390179 | 0.83 | ALOX5 (0.71) | KEAP1MAPTMEN1KMT2ALMNA | |
| SCHEMBL28802349 | 0.80 | GAA (0.44) | HSPA5KEAP1MAPTMEN1KMT2A | |
| SCHEMBL11119190 | 0.79 | ESR1 (0.49) | HSPA5KEAP1MAPTMEN1KMT2A | |
| Bromide SCHEMBL27886793 | 0.79 | GAA (0.43) | HSPA5KEAP1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28104026 | 0.79 | GAA (0.43) | HSPA5KEAP1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945516-A | PRIOR TO ESTERIFICATION OF THE POLYHYDROXY PHENOL WITH THE NAPHTHOQUINONE DIAZIDE SULFONYL HALIDE, THE REACTANTS ARE INITIALLY DISSOLVED IN AN APROTIC SOLVENT TOGETHER WITH STRONG BASE; NONPRECIPITATING, FOR FORMATION OF PHOTORESISTS | SHIPLEY COMPANY, L.L.C. (US) | 1999-08-31 | — | — | US | disclosed |
| US-5821345-A | DISSOLVING WITH A STRONG BASE AND APROTIC SOLVENT; ESTER INTERCHANGE | SHIPLEY COMPANY, L.L.C. (US) | 1998-10-13 | — | — | US | disclosed |