Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 6/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8429870 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL8428785 | 0.92 | ALDH1A1 (0.56) | ALDH1A1TDP1SMN1; SMN2TSHR | |
| SCHEMBL8429868 | 0.89 | ALDH1A1 (0.77) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL24058904 | 0.88 | ALDH1A1 (0.70) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL5692030 | 0.86 | ALDH1A1 (0.46) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| Hexane SCHEMBL5603076 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL24059110 | 0.83 | ALDH1A1 (0.72) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 | |
| Alcohol SCHEMBL9348127 | 0.82 | ALDH1A1 (0.89) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 | |
| Alcohol SCHEMBL4541130 | 0.82 | ALDH1A1 (0.89) | ALDH1A1TDP1SMN1; SMN2TSHRSPHK2 | |
| SCHEMBL12808627 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1TDP1SMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662314-B1 | Method of hair treatment | KAO CORP (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0662314-A1 | Method of hair treatment | Kao Corporation (JP) | 1995-07-12 | — | — | EP | disclosed |