SCHEMBL8430870

SCHEMBL8430870

CC(=O)N(CCCO)CCCO

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
NTRK2 Q16620 1/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA9 Q16790 2/20 0.36
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
CAMK2A Q9UQM7 1/20 0.33
GPR84 Q9NQS5 1/20 0.31
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8631840 0.91 CA12 (0.50) LMNACA12CA1CA9ALDH1A1
SCHEMBL8634539 0.91 CA12 (0.43) USP2LMNANTRK2CA12CA1
SCHEMBL8629998 0.87 CA12 (0.43) USP2LMNANTRK2CA12CA1
SCHEMBL20261072 0.87 LMNA (0.48) LMNACA12CA1CA9ALDH1A1
SCHEMBL25702791 0.87 LMNA (0.48) LMNACA12CA1CA9ALDH1A1
SCHEMBL21870585 0.85 NTRK2 (0.33) USP2LMNANTRK2CA12CA1
SCHEMBL8633186 0.84 CA12 (0.48) LMNACA12CA1CA9ALDH1A1
SCHEMBL8634317 0.84 CA12 (0.41) USP2LMNACA12CA1CA9
SCHEMBL26290425 0.83 MGAM (0.46) USP2LMNANTRK2ALDH1A1KDM4E
SCHEMBL8940796 0.82 MAPT (0.40) USP2LMNACA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5612382-A Composition for percutaneous absorption of pharmaceutically active ingredients Fike, Frances B. (US) 1997-03-18 US claimed
WO-2023250375-A1 CIRCULAR RNA ENCODING CHIMERIC ANTIGEN RECEPTORS TARGETING BCMA ORNA THERAPEUTICS, INC. (US) 2023-12-28 WO disclosed
EP-4289951-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2023-12-13 EP disclosed
WO-2023056033-A1 LIPID NANOPARTICLE COMPOSITIONS FOR DELIVERING CIRCULAR POLYNUCLEOTIDES ORNA THERAPEUTICS, INC. (US) 2023-04-06 WO disclosed
WO-2022261490-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2022-12-15 WO disclosed
WO-2021226597-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2021-11-11 WO disclosed
WO-2021189059-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2021-09-23 WO disclosed
WO-2021113777-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2021-06-10 WO disclosed
WO-2021030701-A1 IMPROVED LIPID NANOPARTICLES FOR DELIVERY OF NUCLEIC ACIDS Acuitas Therapeutics, Inc. (CA) 2021-02-18 WO disclosed
WO-2019036000-A1 LIPIDS FOR USE IN LIPID NANOPARTICLE FORMULATIONS Acuitas Therapeutics, Inc. (CA) 2019-02-21 WO disclosed
CN-102428035-B Halogenated amide biocidal compounds and methods of treating water systems at near neutral to high pH DOW GLOBAL TECHNOLOGIES LLC 2014-07-23 CN disclosed
CN-102428037-B Halogenated amide biocidal compounds and methods for treating water systems at near neutral to high PH DOW GLOBAL TECHNOLOGIES INC 2014-06-11 CN disclosed
WO-2012135669-A1 NITROGEN RING CONTAINING COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS WEINGARTEN M DAVID (US) 2012-10-04 WO disclosed
US-20120238752-A1 COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-8197994-B2 Colorant of a dipyrromethene-based metal complex obtained from a metal of iron, zinc, cobalt, copper or vanadium oxide and a dipyrromethene-based compound and a phthalocyanine dye FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-20120138877-A1 COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
EP-0956318-A1 RADIATION-CURABLE COMPOSITION DSM N.V. (NL) 1999-11-17 EP disclosed
WO-1998033855-A1 RADIATION-CURABLE COMPOSITION DSM N.V. (NL) 1998-08-06 WO disclosed
US-5612382-A Composition for percutaneous absorption of pharmaceutically active ingredients Fike, Frances B. (US) 1997-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238752-A1 COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION PBRM1, CRY1, MAPT USP2 1391/4885LMNA 2333/4885NTRK2 4351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.