SCHEMBL84311

SCHEMBL84311

CCN1C(=O)c2ccc(Oc3ccc(C(C)(C)c4ccc(Oc5ccc6c(c5)C(=O)N(C)C6=O)cc4)cc3)cc2C1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 2/20 0.49
MEN1 O00255 2/20 0.49
HTT P42858 1/20 0.49
LPAR1 Q92633 1/20 0.48
LPAR3 Q9UBY5 1/20 0.48
HSD17B10 Q99714 3/20 0.48
MAPK1 P28482 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
POLB P06746 3/20 0.43
APAF1 O14727 1/20 0.41
HPGD P15428 2/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
APP P05067 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
PKM P14618 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13928043 0.91 ALDH1A1 (0.57) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL84288 0.91 ALDH1A1 (0.47) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL30237601 0.91 ALDH1A1 (0.47) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL19499368 0.89 ALDH1A1 (0.59) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL13899502 0.87 LPAR1 (0.52) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL13923539 0.85 APP (0.55) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL22946547 0.84 ALDH1A1 (0.48) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL13928044 0.84 ALDH1A1 (0.51) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL13427347 0.83 LPAR3 (0.43) ALDH1A1KMT2AKDM4EMEN1HTT
SCHEMBL13972680 0.83 ALDH1A1 (0.41) ALDH1A1KMT2AKDM4EMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170306094-A1 POLYIMIDE COPOLYMER AND MOLDED ARTICLE USING SAME SOMAR CORPORATION (JP) 2017-10-26 US disclosed
US-8792318-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-07-29 US disclosed
US-20120155242-A1 METHOD FOR HIGH DENSITY DATA STORAGE AND IMAGING INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-06-21 US disclosed
US-8129496-B2 Method for high density data storage and imaging INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-06 US disclosed
US-7491447-B2 Double-sided metallic laminate and method for manufacturing the same LG CHEM, LTD. (KR) 2009-02-17 US disclosed
US-20090035591-A1 FLEXIBLE LAMINATE HAVING THERMOPLASTIC POLYIMIDE LAYER AND METHOD FOR MANUFACTURING THE SAME KURASHIKI BOSEKI KABUSHIKI KAISHA (JP) 2009-02-05 US disclosed
US-20070042202-A1 Double-sided metallic laminate and method for manufacturing the same LG CHEM, LTD. (KR) 2007-02-22 US disclosed