SCHEMBL13928043

SCHEMBL13928043

CCN1C(=O)c2ccc(Oc3ccc(Oc4ccc(Oc5ccc6c(c5)C(=O)N(C)C6=O)cc4)cc3)cc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.57
KDM4E B2RXH2 3/20 0.57
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
HTT P42858 1/20 0.57
HSD17B10 Q99714 3/20 0.56
MAPK1 P28482 2/20 0.56
LPAR3 Q9UBY5 2/20 0.56
LPAR1 Q92633 1/20 0.56
TDP1 Q9NUW8 1/20 0.55
POLB P06746 3/20 0.49
APAF1 O14727 1/20 0.47
HPGD P15428 3/20 0.46
MAPT P10636 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
APP P05067 1/20 0.46
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19499368 0.98 ALDH1A1 (0.59) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL13928044 0.93 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL84311 0.91 ALDH1A1 (0.49) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL14106913 0.88 ALDH1A1 (0.56) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL22681991 0.87 ALDH1A1 (0.69) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL262253 0.87 ALDH1A1 (0.57) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL12736627 0.86 POLB (0.48) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL23240780 0.84 ALDH1A1 (0.50) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL8737302 0.83 LPAR1 (0.61) ALDH1A1KDM4EKMT2AMEN1HTT
SCHEMBL18117700 0.83 ALDH1A1 (0.51) ALDH1A1KDM4EKMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090035591-A1 FLEXIBLE LAMINATE HAVING THERMOPLASTIC POLYIMIDE LAYER AND METHOD FOR MANUFACTURING THE SAME KURASHIKI BOSEKI KABUSHIKI KAISHA (JP) 2009-02-05 US disclosed