Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 6/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15873920 | 0.75 | KDM4A (0.41) | CACNA1HCACNA1BCACNA1CKDM4ANSD2 | |
| SCHEMBL16808752 | 0.74 | MTNR1A (0.47) | CACNA1HCACNA1BCACNA1CKDM4ANSD2 | |
| SCHEMBL20843663 | 0.72 | SETDB1 (0.42) | KDM4ANSD2CTSSCTSK | |
| SCHEMBL31130004 | 0.72 | SETDB1 (0.42) | KDM4ANSD2CTSSCTSK | |
| SCHEMBL25155252 | 0.71 | SMN1; SMN2 (0.44) | CACNA1HCACNA1BCACNA1CKDM4AKDM4E | |
| SCHEMBL30469092 | 0.70 | KDM4A (0.54) | CACNA1HCACNA1BCACNA1CKDM4ABCHE | |
| SCHEMBL25677972 | 0.70 | KDM4A (0.54) | CACNA1HCACNA1BCACNA1CKDM4ABCHE | |
| SCHEMBL4145619 | 0.70 | KDM4A (0.47) | KDM4ANSD2KDM4ELMNAL3MBTL1 | |
| SCHEMBL25155486 | 0.70 | SMN1; SMN2 (0.46) | CACNA1HCACNA1BCACNA1CKDM4AKDM4E | |
| SCHEMBL15444663 | 0.69 | SMN1; SMN2 (0.42) | CACNA1HCACNA1BCACNA1CKDM4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956294-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998006741-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |