SCHEMBL8431335

C[C@H](N)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.47

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	12/20	0.47

▸	CALCR	P30988	12/20	0.47

▸	OPRL1	P41146	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8429395	0.95	OPRL1 (0.45)	RAMP3CALCROPRL1
SCHEMBL29815704	0.89	KEAP1 (0.43)	RAMP3CALCR
SCHEMBL8429424	0.86	NPY4R (0.60)	RAMP3CALCR
SCHEMBL29823853	0.86	EGFR (0.43)	—
SCHEMBL29689021	0.85	RAMP3 (0.49)	RAMP3CALCR
SCHEMBL31674373	0.84	NPY4R (0.44)	—
SCHEMBL30140925	0.84	TFPI (0.43)	—
SCHEMBL31319515	0.84	RAMP3 (0.48)	RAMP3CALCR
SCHEMBL30140864	0.84	BACE1 (0.43)	RAMP3CALCR
SCHEMBL8429823	0.84	NPY5R (0.46)	OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5859187-A	Antiviral peptides	E. R. SQUIBB & SONS, INC. (US)	1999-01-12	—	—	US	disclosed