SCHEMBL8429395

C[C@H](N)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.48

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	OPRL1	P41146	5/20	0.45

▸	NPY5R	Q15761	3/20	0.44

▸	NPY1R	P25929	2/20	0.44

▸	NPY4R	P50391	2/20	0.44

▸	KEAP1	Q14145	2/20	0.44

▸	TFPI	P10646	1/20	0.44

▸	RAMP3	O60896	3/20	0.43

▸	CALCR	P30988	3/20	0.43

▸	IL23R	Q5VWK5	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8431335	0.95	RAMP3 (0.47)	OPRL1RAMP3CALCR
SCHEMBL8429424	0.90	NPY4R (0.60)	NPY5RNPY1RNPY4RTFPIRAMP3
SCHEMBL8429823	0.89	NPY5R (0.46)	OPRL1NPY5RNPY1RNPY4RTFPI
SCHEMBL29815704	0.83	KEAP1 (0.43)	KEAP1RAMP3CALCR
SCHEMBL31437186	0.83	NOD1 (0.47)	NPY5RNPY1RNPY4RKEAP1TFPI
SCHEMBL29689021	0.82	RAMP3 (0.49)	NPY5RNPY1RNPY4RRAMP3CALCR
SCHEMBL30599807	0.81	OPRL1 (0.43)	OPRL1IL23R
SCHEMBL30773898	0.81	NPY4R (0.48)	NPY5RNPY1RNPY4R
SCHEMBL30773902	0.81	NPY4R (0.48)	NPY5RNPY1RNPY4R
SCHEMBL16507759	0.81	TFPI (0.50)	OPRL1KEAP1TFPIIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5859187-A	Antiviral peptides	E. R. SQUIBB & SONS, INC. (US)	1999-01-12	—	—	US	disclosed