Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | HK1 | P19367 | 2/20 | 0.35 |
| ▸ | HK2 | P52789 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431497 | 1.00 | LGALS3 (0.42) | LGALS3SMPD1CNR2CA1CA2 | |
| SCHEMBL9514287 | 0.93 | TLR4 (0.41) | LGALS3SMPD1CNR2TLR4 | |
| SCHEMBL9515118 | 0.92 | TLR4 (0.44) | LGALS3SMPD1CNR2TLR4 | |
| SCHEMBL9515090 | 0.92 | TLR4 (0.44) | LGALS3SMPD1CNR2TLR4 | |
| SCHEMBL9511882 | 0.90 | SMPD1 (0.43) | LGALS3SMPD1CNR2CA1CA2 | |
| SCHEMBL9511499 | 0.84 | SMPD1 (0.40) | LGALS3SMPD1CNR2S1PR3S1PR1 | |
| SCHEMBL9514279 | 0.83 | SMPD1 (0.42) | LGALS3SMPD1CNR2CA1CA2 | |
| SCHEMBL9513498 | 0.83 | SMPD1 (0.42) | SMPD1CNR2CA1CA2CA9 | |
| SCHEMBL9511533 | 0.83 | TLR4 (0.48) | LGALS3SMPD1CA1CA2CA9 | |
| SCHEMBL10417944 | 0.83 | TLR4 (0.48) | LGALS3SMPD1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | claimed |
| EP-0288888-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | claimed |
| US-RE36385-E | TREATMENT OF TUMORS, ENHANCING IMMUNITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| US-4925929-A | ANTITUMOR AGENTS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1990-05-15 | — | — | US | disclosed |