Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 12/20 | 0.41 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431497 | 0.93 | LGALS3 (0.42) | TLR4LGALS3SMPD1CNR2 | |
| SCHEMBL8431503 | 0.93 | LGALS3 (0.42) | TLR4LGALS3SMPD1CNR2 | |
| SCHEMBL10419809 | 0.88 | SMPD1 (0.33) | TLR4LY96SMPD1CNR2 | |
| SCHEMBL10419810 | 0.88 | SMPD1 (0.33) | TLR4LY96SMPD1CNR2 | |
| SCHEMBL9515090 | 0.88 | TLR4 (0.44) | TLR4LY96LGALS3SMPD1CNR2 | |
| SCHEMBL9515118 | 0.88 | TLR4 (0.44) | TLR4LY96LGALS3SMPD1CNR2 | |
| SCHEMBL8431664 | 0.85 | TLR4 (0.45) | TLR4LY96 | |
| SCHEMBL9511882 | 0.83 | SMPD1 (0.43) | TLR4LY96LGALS3SMPD1CNR2 | |
| SCHEMBL9511499 | 0.81 | SMPD1 (0.40) | TLR4LY96LGALS3SMPD1CNR2 | |
| SCHEMBL6795699 | 0.80 | TLR4 (0.60) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288888-B1 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO (JP) | 1993-12-08 | — | — | EP | claimed |
| EP-0288888-A2 | Novel glucopyranose derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | claimed |