Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050021 | 0.85 | L3MBTL1 (0.67) | GAAKDM4EL3MBTL1KMT2AHTT | |
| SCHEMBL11582104 | 0.83 | GAA (0.41) | GAAKDM4EL3MBTL1KMT2AHTT | |
| SCHEMBL27823770 | 0.82 | KIF11 (0.53) | GAAKDM4EL3MBTL1KMT2AHTT | |
| SCHEMBL8436453 | 0.80 | L3MBTL1 (0.71) | GAAKDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL11883866 | 0.80 | L3MBTL1 (0.46) | GAAKDM4EL3MBTL1KMT2AHTT | |
| SCHEMBL6694336 | 0.80 | RXFP1 (0.53) | GAAKDM4EKMT2AHTTMEN1 | |
| SCHEMBL29840068 | 0.80 | GAA (0.67) | GAAKDM4EKMT2AHTTMEN1 | |
| SCHEMBL3928666 | 0.80 | GAA (0.67) | GAAKDM4EKMT2AHTTMEN1 | |
| SCHEMBL15952997 | 0.79 | NPC1 (0.57) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL29221018 | 0.79 | PDCD1 (0.48) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942536-A | USEFUL FOR TREATING MIGRAINE | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |