Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407940 | 0.89 | NPC1 (0.54) | NPC1MRGPRX4RAB9ABRD4SGMS2 | |
| SCHEMBL2894833 | 0.85 | NPC1 (0.50) | NPC1MRGPRX4RAB9ABRD4SGMS2 | |
| Hydrochloric Acid SCHEMBL28557881 | 0.78 | NPC1 (0.48) | NPC1MRGPRX4RAB9ABRD4SGMS2 | |
| SCHEMBL8405081 | 0.77 | NPC1 (0.53) | NPC1MRGPRX4RAB9ABRD4SGMS2 | |
| SCHEMBL705457 | 0.77 | MGLL (0.58) | NPC1MGLLRAB9APOLBSMN1; SMN2 | |
| SCHEMBL2892753 | 0.76 | NPC1 (0.52) | NPC1MRGPRX4RAB9ABRD4SGMS2 | |
| SCHEMBL2892814 | 0.76 | NPC1 (0.55) | NPC1MRGPRX4MEN1KMT2ALMNA | |
| SCHEMBL21862932 | 0.75 | NPC1 (0.45) | NPC1MRGPRX4RAB9ABRD4SGMS2 | |
| SCHEMBL12474651 | 0.75 | MGLL (0.51) | NPC1MGLLRAB9APOLBSMN1; SMN2 | |
| SCHEMBL2897224 | 0.74 | MRGPRX4 (0.62) | NPC1MRGPRX4MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624567-B1 | Derivatives of 3-fluorophenol, process for their preparation and their use | CLARIANT GMBH (DE) | 1999-12-08 | — | — | EP | claimed |
| EP-0624567-A2 | Derivatives of 3-fluorophenol, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-17 | — | — | EP | claimed |
| EP-0624567-B1 | Derivatives of 3-fluorophenol, process for their preparation and their use | CLARIANT GMBH (DE) | 1999-12-08 | — | — | EP | disclosed |
| EP-0624567-A2 | Derivatives of 3-fluorophenol, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-17 | — | — | EP | disclosed |