Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436002 | 0.89 | ESR1 (0.35) | ESR1ESR2ALDH1A1MAPTKMT2A | |
| SCHEMBL9910783 | 0.80 | ESR1 (0.43) | ESR1ESR2ALDH1A1MAPTPOLB | |
| SCHEMBL8432092 | 0.80 | ESR1 (0.46) | ESR1ESR2ALDH1A1MAPTPOLB | |
| SCHEMBL9204049 | 0.80 | HTT (0.40) | ESR1ESR2ALDH1A1MAPTPOLB | |
| SCHEMBL8431885 | 0.78 | HSD17B10 (0.51) | ALDH1A1MAPTPOLBKMT2AMEN1 | |
| SCHEMBL7096170 | 0.76 | NR1H2 (0.47) | KMT2AMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL9199887 | 0.76 | HTT (0.41) | ESR1ESR2ALDH1A1MAPTPOLB | |
| SCHEMBL2997187 | 0.76 | KLF10 (0.46) | ESR1ESR2ALDH1A1MAPTPOLB | |
| SCHEMBL11511323 | 0.76 | ALDH1A1 (0.48) | ESR1ESR2ALDH1A1MAPTPOLB | |
| SCHEMBL30806220 | 0.76 | KLF10 (0.46) | ESR1ESR2ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605404-B1 | Polycyclic dyes | BASF AG (DE) | 1999-12-08 | — | — | EP | disclosed |
| EP-0363034-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1995-01-04 | — | — | EP | disclosed |
| EP-0605404-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1994-07-06 | — | — | EP | disclosed |
| EP-0570111-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |
| US-5212313-A | For polyester | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-18 | — | — | US | disclosed |
| US-5183888-A | Reacting a phenyl tartronic acid with a dihydrobenzofuran, oxidizing, to get dihydrobenzodifuran | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-02 | — | — | US | disclosed |
| US-5084580-A | Aniline dyes for polyester fabrics to give green and blue color | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0363034-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |