Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 19/20 | 0.61 |
| ▸ | ADAM17 | P78536 | 14/20 | 0.61 |
| ▸ | MMP13 | P45452 | 6/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432172 | 1.00 | MMP1 (0.61) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL8436082 | 0.92 | MMP1 (0.51) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL8436089 | 0.92 | MMP1 (0.51) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL8435351 | 0.90 | MMP1 (0.66) | MMP1ADAM17MMP13MMP3 | |
| SCHEMBL8435353 | 0.90 | MMP1 (0.66) | MMP1ADAM17MMP13MMP3 | |
| SCHEMBL7111222 | 0.86 | MMP1 (0.66) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL8521493 | 0.85 | ADAM17 (0.49) | MMP1ADAM17MMP13 | |
| SCHEMBL8521491 | 0.85 | ADAM17 (0.49) | MMP1ADAM17MMP13 | |
| SCHEMBL8570605 | 0.83 | ADAM17 (0.47) | MMP1ADAM17MMP13MMP3 | |
| SCHEMBL8570608 | 0.83 | ADAM17 (0.47) | MMP1ADAM17MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960098-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998034918-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-08-13 | — | — | WO | disclosed |