Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638442 | 0.82 | CA2 (0.57) | ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL9079364 | 0.82 | CES1 (0.54) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL7147959 | 0.81 | ALDH1A1 (0.56) | ALDH1A1PLK1SMN1; SMN2LMNARAB9A | |
| SCHEMBL8603800 | 0.79 | NPC1 (0.42) | ALDH1A1PLK1SMN1; SMN2LMNARAB9A | |
| SCHEMBL29158541 | 0.78 | PLK1 (0.46) | ALDH1A1PLK1SMN1; SMN2LMNARAB9A | |
| SCHEMBL7149195 | 0.77 | ALDH1A1 (0.52) | ALDH1A1PLK1SMN1; SMN2LMNARAB9A | |
| SCHEMBL29158545 | 0.77 | PLK1 (0.44) | ALDH1A1PLK1SMN1; SMN2LMNARAB9A | |
| SCHEMBL10140460 | 0.77 | CYP4F2 (0.50) | ALDH1A1PLK1SMN1; SMN2LMNARAB9A | |
| SCHEMBL156207 | 0.74 | ALDH1A1 (0.63) | ALDH1A1PLK1LMNAHPGDPOLB | |
| SCHEMBL4541922 | 0.74 | ALDH1A1 (0.48) | ALDH1A1PLK1SMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |