Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432296 | 0.88 | TP53 (0.50) | MEN1KMT2AMAPTTP53ADRB2 | |
| SCHEMBL9005298 | 0.88 | SLC6A9 (0.39) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL8430938 | 0.82 | MEN1 (0.50) | MEN1KMT2AMAPTTP53ADRB2 | |
| SCHEMBL8434409 | 0.78 | MEN1 (0.56) | MEN1KMT2AMAPTTP53ADRB2 | |
| SCHEMBL9005297 | 0.78 | SLC6A9 (0.42) | MEN1KMT2AMAPTTP53ABCB1 | |
| SCHEMBL8430964 | 0.73 | MEN1 (0.40) | MEN1KMT2AMAPTTP53ADRB2 | |
| SCHEMBL8432829 | 0.69 | TP53 (0.65) | MEN1KMT2AMAPTTP53ABCB1 | |
| SCHEMBL9005294 | 0.68 | SLC6A9 (0.43) | MEN1KMT2AMAPTTP53ABCB1 | |
| SCHEMBL8006361 | 0.68 | KCNH2 (0.67) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL12576516 | 0.68 | MAPT (0.57) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981530-A | FOR TREATMENT OF ALLERGIC DISEASES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |