Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005292 | 0.91 | MEN1 (0.41) | SLC6A9HSP90AB1ABCB1MEN1KMT2A | |
| SCHEMBL8430938 | 0.87 | MEN1 (0.50) | SLC6A9HSP90AB1ABCB1MEN1KMT2A | |
| SCHEMBL9005296 | 0.86 | HSP90AB1 (0.51) | HSP90AB1ABCB1TP53MAPT | |
| SCHEMBL9005297 | 0.86 | SLC6A9 (0.42) | SLC6A9HSP90AB1ABCB1MEN1KMT2A | |
| SCHEMBL9005298 | 0.80 | SLC6A9 (0.39) | SLC6A9HSP90AB1MEN1KMT2ATP53 | |
| SCHEMBL8434409 | 0.79 | MEN1 (0.56) | HSP90AB1ABCB1MEN1KMT2ATP53 | |
| SCHEMBL9005291 | 0.78 | ABCB1 (0.48) | HSP90AB1ABCB1MEN1KMT2ATP53 | |
| SCHEMBL8430964 | 0.76 | MEN1 (0.40) | SLC6A9HSP90AB1ABCB1MEN1KMT2A | |
| SCHEMBL8432296 | 0.75 | TP53 (0.50) | SLC6A9HSP90AB1ABCB1MEN1KMT2A | |
| SCHEMBL8432829 | 0.72 | TP53 (0.65) | HSP90AB1ABCB1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | claimed |
| EP-0735030-A1 | Piperazine derivative having antiallergic activity | Senju Pharmaceutical Co., Ltd. (JP) | 1996-10-02 | — | — | EP | disclosed |