Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604264 | 0.84 | KMT2A (0.44) | TRPA1RIPK1HPGDALDH1A1RAB9A | |
| SCHEMBL17123620 | 0.83 | RIPK1 (0.46) | TRPA1RIPK1HPGDALDH1A1 | |
| SCHEMBL16523042 | 0.79 | TRPA1 (0.41) | TRPA1RIPK1HPGDALDH1A1 | |
| SCHEMBL585429 | 0.77 | TRPA1 (0.48) | TRPA1RIPK1HPGDRAB9ANPC1 | |
| SCHEMBL13202632 | 0.75 | FABP7 (0.39) | TRPA1RIPK1HPGDALDH1A1 | |
| SCHEMBL12258178 | 0.75 | HPGD (0.46) | TRPA1RIPK1HPGDALDH1A1RAB9A | |
| SCHEMBL4270025 | 0.74 | TAAR1 (0.47) | TRPA1RIPK1 | |
| SCHEMBL17880780 | 0.74 | TRPA1 (0.46) | TRPA1RIPK1HPGDALDH1A1RAB9A | |
| SCHEMBL19757388 | 0.74 | TRPA1 (0.37) | TRPA1RIPK1HPGDALDH1A1 | |
| SCHEMBL25548120 | 0.74 | TSHR (0.45) | HPGDALDH1A1RAB9ANPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129505-B2 | Formed by catalytic polymerization; antibody conjugates | UCB PHARMA S.A. (BE) | 2012-03-06 | — | — | US | disclosed |
| US-20080220005-A1 | Comb Polymers | UCB PHARMA S.A. (BE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220005-A1 | Comb Polymers | C9, F13B, PYM1 | TRPA1 4686/4885RIPK1 1805/4885MME 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.