Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9794754 | 0.98 | GAA (0.47) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL17931106 | 0.86 | RECQL (0.42) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL8434608 | 0.83 | GAA (0.50) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL4533799 | 0.82 | GAA (0.46) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL4541846 | 0.81 | GAA (0.42) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL8762446 | 0.79 | GAA (0.47) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL8432690 | 0.79 | SLC2A1 (0.50) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL11652673 | 0.79 | GAA (0.47) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL39399 | 0.79 | SLC2A1 (0.44) | GAAKDM4ELMNAALDH1A1NPSR1 | |
| SCHEMBL11210685 | 0.78 | KMT2A (0.41) | GAAKDM4ELMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508181-A1 | Hybrid process for preparing a tri-substituted triazine | THE B.F. GOODRICH COMPANY (US) | 1992-10-14 | — | — | EP | claimed |
| US-20210284660-A1 | HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. | 2021-09-16 | — | — | US | disclosed |
| US-8461235-B2 | Use of polymer powder containing UV absorber for the stabilisation of polymers against the effects of UV radiation | BASF SE (DE) | 2013-06-11 | — | — | US | disclosed |
| US-8119654-B2 | Indenoisoquinolinone analogs and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-8119654-B2 | Indenoisoquinolinone analogs and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100179140-A1 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2010-07-15 | — | — | US | disclosed |
| US-20100179140-A1 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2010-07-15 | — | — | US | disclosed |
| US-7745641-B2 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7745641-B2 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7728057-B2 | Use of polymer powder containing UV absorber for the stabilisation of polymers against the effects of UV radiation | BASF AKTIENGESELLSCHAFT (DE) | 2010-06-01 | — | — | US | disclosed |
| US-4618634-A | 2,2,6,6-TETRAMETHYLPIPERIDIN-4YL)ALKOXY-AMIDES | CIBA-GEIGY S.P.A. (IT) | 1986-10-21 | — | — | US | disclosed |
| US-4477615-A | Polypiperidinyl stabilizing agents for polymer materials | APITAL PRODUZIONI INDUSTRIALI S.P.A. (IT) | 1984-10-16 | — | — | US | disclosed |
| EP-0117229-A1 | Piperidinyl-triazine compounds, for use as stabilizers for synthetic polymers | CIBA-GEIGY S.p.A. (IT) | 1984-08-29 | — | — | EP | disclosed |
| US-4442250-A | HEAT, LIGHT, AND OXIDATION RESISTANCE | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1984-04-10 | — | — | US | disclosed |
| US-4386127-A | SYNTHETIC LEATHER; SUEDE | TORAY INDUSTRIES, INC. (JP) | 1983-05-31 | — | — | US | disclosed |
| US-4348524-A | LIGHT STABILIZERS FOR POLYPROPYLENE | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| US-4302493-A | Dense, elegant and pliable sheet material comprising fibrous base impregnated with a diol-hindered amine polyurethane system | TORAY INDUSTRIES, INCORPORATED (JP) | 1981-11-24 | — | — | US | disclosed |
| US-4263434-A | UV STABILIZERS FOR POLYMERS | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1981-04-21 | — | — | US | disclosed |
| US-4108829-A | PHOTOSTABILITY | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1978-08-22 | — | — | US | disclosed |
| US-4086204-A | LIGHT STABILIZERS | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179140-A1 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | TNNI3, IDH2, GLS | GAA 2521/4885KDM4E 2660/4885LMNA 407/4885 |
| US-20210284660-A1 | HETEROARYL COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, HDAC6 | GAA 16/4885KDM4E 3075/4885LMNA 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.