Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.59 |
| ▸ | CES1 | P23141 | 8/20 | 0.59 |
| ▸ | CES2 | O00748 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573096 | 0.98 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL638951 | 0.98 | FAAH (0.61) | FAAHCES1CES2MEN1KMT2A | |
| Fluoride SCHEMBL10493503 | 0.95 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Water SCHEMBL11595702 | 0.95 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Bromide SCHEMBL6552300 | 0.95 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL196410 | 0.95 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL219232 | 0.95 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Bromide SCHEMBL1244460 | 0.95 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Water SCHEMBL3120172 | 0.95 | FAAH (0.59) | FAAHCES1CES2MEN1KMT2A | |
| Bicarbonate SCHEMBL28167556 | 0.93 | FAAH (0.57) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074794-B | Method for producing polyvalent glycidyl compound | 昭和电工株式会社 | 2019-09-24 | — | — | CN | disclosed |
| CN-108884185-A | Process for producing epoxidized polymer | 库珀轮胎和橡胶公司 | 2018-11-23 | — | — | CN | disclosed |
| EP-3135677-B1 | ALICYCLIC DIEPOXY COMPOUND HAVING BIS-SPIRONORBORNANE STRUCTURE, METHOD FOR PRODUCING SAME, AND USE FOR SAME | JX NIPPON OIL & ENERGY CORP (JP) | 2018-10-10 | — | — | EP | disclosed |
| CN-107074794-A | Method for producing polyvalent glycidyl compound | 昭和电工株式会社 | 2017-08-18 | — | — | CN | disclosed |
| US-9695186-B2 | Alicyclic diepoxy compound having bis-spironorbornane structure, method for producing the same, and use thereof | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| CN-106661046-A | Alicyclic diepoxy compound having a double-spironorbornane structure, process for producing the same, and use thereof | 捷客斯能源株式会社 | 2017-05-10 | — | — | CN | disclosed |
| EP-3135677-A1 | ALICYCLIC DIEPOXY COMPOUND HAVING BIS-SPIRONORBORNANE STRUCTURE, METHOD FOR PRODUCING SAME, AND USE FOR SAME | JX Nippon Oil & Energy Corporation (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-20170044179-A1 | ALICYCLIC DIEPOXY COMPOUND HAVING BIS-SPIRONORBORNANE STRUCTURE, METHOD FOR PRODUCING THE SAME, AND USE THEREOF | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |
| CN-104892611-A | Synthetic method of caffeine | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-09-09 | — | — | CN | disclosed |
| US-5856519-A | 2-HYDROXY-2-(ALKYL OR CYCLOHEXYL)-N,N-BUTYLENEACETAMIDE | MERCK & CO., INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0869950-A1 | STEREOSELECTIVE PROCESS | Merck & Co., Inc. (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5708186-A | MULTISTAGE REACTION ALKYLATION IN SOLVENT | MERCK & CO., INC. | 1998-01-13 | — | — | US | disclosed |
| WO-1997021693-A1 | STEREOSELECTIVE PROCESS | MERCK & CO., INC. (US) | 1997-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044179-A1 | ALICYCLIC DIEPOXY COMPOUND HAVING BIS-SPIRONORBORNANE STRUCTURE, METHOD FOR PRODUCING THE SAME, AND USE THEREOF | DHCR7, HSD17B7, CYP17A1 | FAAH 3761/4885CES1 1261/4885CES2 3920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.