Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431885 | 0.83 | HSD17B10 (0.51) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL17416735 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL8433249 | 0.80 | MAPT (0.42) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL8432092 | 0.79 | ESR1 (0.46) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL19261801 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL15456896 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL7097334 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL8432173 | 0.75 | ESR1 (0.40) | ALDH1A1HSD17B10HTTKDM4ESMN1; SMN2 | |
| SCHEMBL1143325 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL8136159 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605404-B1 | Polycyclic dyes | BASF AG (DE) | 1999-12-08 | — | — | EP | disclosed |
| EP-0363034-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1995-01-04 | — | — | EP | disclosed |
| EP-0605404-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1994-07-06 | — | — | EP | disclosed |
| EP-0570111-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |
| US-5212313-A | For polyester | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-18 | — | — | US | disclosed |
| US-5183888-A | Reacting a phenyl tartronic acid with a dihydrobenzofuran, oxidizing, to get dihydrobenzodifuran | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-02 | — | — | US | disclosed |
| US-5084580-A | Aniline dyes for polyester fabrics to give green and blue color | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0363034-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |