Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807221 | 0.83 | LMNA (0.35) | LMNAMGAMTHRBL3MBTL1USP2 | |
| SCHEMBL3181945 | 0.83 | LMNA (0.35) | LMNAMGAMTHRBL3MBTL1USP2 | |
| SCHEMBL1184726 | 0.83 | MGAM (0.41) | LMNAMGAMTHRBUSP2 | |
| SCHEMBL12180777 | 0.81 | MGAM (0.45) | LMNAMGAMTHRBL3MBTL1 | |
| SCHEMBL4361137 | 0.81 | MGAM (0.45) | LMNAMGAMTHRBL3MBTL1 | |
| SCHEMBL13358959 | 0.81 | MGAM (0.45) | LMNAMGAMTHRBL3MBTL1 | |
| SCHEMBL12657731 | 0.81 | MGAM (0.45) | LMNAMGAMTHRBL3MBTL1 | |
| Methoxymethane SCHEMBL27543746 | 0.80 | LMNA (0.36) | LMNAMGAMTHRBL3MBTL1 | |
| SCHEMBL2829022 | 0.79 | LMNA (0.39) | LMNAMGAMTHRBL3MBTL1 | |
| SCHEMBL4507262 | 0.79 | LMNA (0.35) | LMNAMGAML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956047-A1 | NEW CARRIER SYSTEMS | IPR-Institute for Pharmaceutical Research Riehen AG (CH) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998016251-A1 | NEW CARRIER SYSTEMS | IPR-INSTITUTE FOR PHARMACEUTICAL RESEARCH AG (CH) | 1998-04-23 | — | — | WO | disclosed |