SCHEMBL8433381

SCHEMBL8433381

CNC(=O)/C(=N\OC)c1cccc(Cl)c1CO

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
HIF1A Q16665 3/20 0.36
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
PKM P14618 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 3/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 1/20 0.34
AKR1B1 P15121 1/20 0.34
TSHR P16473 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8338404 1.00 KMT2A (0.39) KMT2AHIF1ATP53CYP1A2PKM
SCHEMBL25667252 0.85 HIF1A (0.36) KMT2AHIF1ACYP1A2CYP2C19ALDH1A1
SCHEMBL8437031 0.84 GAA (0.39) KMT2AHIF1ATP53PKMALDH1A1
SCHEMBL8336671 0.84 GAA (0.39) KMT2AHIF1ATP53PKMALDH1A1
SCHEMBL6719570 0.78 HIF1A (0.46) HIF1ATP53ALDH1A1GAA
SCHEMBL6721998 0.78 HIF1A (0.46) HIF1ATP53ALDH1A1GAA
SCHEMBL6719571 0.78 HIF1A (0.46) HIF1ATP53ALDH1A1GAA
SCHEMBL27208804 0.77 ALDH1A1 (0.38) KMT2AHIF1ACYP1A2PKMCYP2C19
Methyl Alcohol SCHEMBL8502229 0.77 HIF1A (0.45) HIF1ATP53ALDH1A1GAA
Methyl Alcohol SCHEMBL8502232 0.77 HIF1A (0.45) HIF1ATP53ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1126742-C fungicidal compounds DOW AGROSCIENCES CORP (US) 2003-11-05 CN disclosed
CN-1246849-A 2-methoxyimino-2- (pyridyloxymethyl) phenylacetamide fungicides having carboxylic acid substituents on the pyridine ring DOW AGROSCIENCES CORP (US) 2000-03-08 CN disclosed
EP-0961771-A1 2-METHOXYIMINO-2-(PYRIDINYLOXYMETHYL)PHENYL ACETAMIDES WITH CARBOXYLIC ACID DERIVATIVES ON THE PYRIDINE RING AS FUNGICIDES Dow AgroSciences LLC (US) 1999-12-08 EP disclosed
WO-1998033772-A1 2-METHOXYIMINO-2-(PYRIDINYLOXYMETHYL)PHENYL ACETAMIDES WITH CARBOXYLIC ACID DERIVATIVES ON THE PYRIDINE RING AS FUNGICIDES DOW AGROSCIENCES LLC (US) 1998-08-06 WO disclosed