SCHEMBL8433528

SCHEMBL8433528

COC(=O)CCN(CCCCCCN(CCC(=O)OC)C1CC(C)(C)NC(C)(C)C1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM5A P29375 2/20 0.35
TSHR P16473 3/20 0.35
EPHX2 P34913 3/20 0.35
GAA P10253 1/20 0.33
USP2 O75604 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8532386 0.93 MEN1 (0.41) MEN1KMT2ATSHREPHX2GAA
SCHEMBL13160772 0.87 EPHX2 (0.31) TSHREPHX2
SCHEMBL8531737 0.87 GAA (0.35) KMT2AKDM5AGAAPOLB
SCHEMBL8534785 0.86 LMNA (0.40) EPHX2GAAALDH1A1LMNA
SCHEMBL8949259 0.86 GAA (0.39) GAA
SCHEMBL8535439 0.86 EPHX2 (0.36) MEN1KMT2ATSHREPHX2GAA
SCHEMBL8435407 0.85 EPHX2 (0.38) EPHX2GAA
SCHEMBL8535940 0.84 EPHX2 (0.39) EPHX2USP2L3MBTL1ALDH1A1
SCHEMBL8532522 0.83 EPHX2 (0.40) EPHX2
SCHEMBL8949295 0.82 GAA (0.32) MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714612-A LIGHT STABILIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-03 US claimed
US-5506286-A BLENDING STABILZER WITH SYNTHETIC RESINS, RUBBERS, PAINTS, OILS TO STABILIZE FROM PHOTOOXIDATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-09 US claimed
US-5384348-A Improved photostability for polymers, weather resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-24 US claimed
JP-6025167-A None JP disclosed
EP-0641822-B1 Thermoplastic resin composition SUMITOMO CHEMICAL CO (JP) 1999-12-01 EP disclosed
US-5714612-A LIGHT STABILIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-03 US disclosed
US-5506286-A BLENDING STABILZER WITH SYNTHETIC RESINS, RUBBERS, PAINTS, OILS TO STABILIZE FROM PHOTOOXIDATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-09 US disclosed
US-5478873-A Polyphenylene ether resin stabilized by 4-amino-2,2,6,6-tetramethylpiperidyl compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-12-26 US disclosed
EP-0641822-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-08 EP disclosed
US-5384348-A Improved photostability for polymers, weather resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-24 US disclosed
JP-H0625167-A STABILIZATION OF ORGANIC MATERIALS WITH HINDERED PIPERIDINE AND ITS PREPARATION THEREOF SUMITOMO CHEM CO LTD 1994-02-01 JP disclosed