Sugi Predict

Sugi Predict / Compounds / SCHEMBL8435407

SCHEMBL8435407

SCHEMBL8435407

CC1(C)CC(N(CCCCCCN(CCC(=O)OC(C)(C)C)C2CC(C)(C)NC(C)(C)C2)CCC(=O)OC(C)(C)C)CC(C)(C)N1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 1/20 0.38
▸ GAA P10253 1/20 0.32
▸ HDAC1 Q13547 1/20 0.31
▸ HDAC2 Q92769 1/20 0.31
▸ HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433528 0.85 MEN1 (0.38) EPHX2GAA
SCHEMBL8534785 0.83 LMNA (0.40) EPHX2GAA
SCHEMBL8949259 0.83 GAA (0.39) GAA
SCHEMBL8535439 0.83 EPHX2 (0.36) EPHX2GAA
SCHEMBL8535940 0.81 EPHX2 (0.39) EPHX2
SCHEMBL8531737 0.80 GAA (0.35) GAA
SCHEMBL8532522 0.80 EPHX2 (0.40) EPHX2
SCHEMBL8535963 0.79 EPHX2 (0.42) EPHX2
SCHEMBL8534147 0.79 NAAA (0.47) GAA
SCHEMBL8534959 0.79 EPHX2 (0.42) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641822-B1 Thermoplastic resin composition SUMITOMO CHEMICAL CO (JP) 1999-12-01 — — EP disclosed
US-5478873-A Polyphenylene ether resin stabilized by 4-amino-2,2,6,6-tetramethylpiperidyl compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-12-26 — — US disclosed
EP-0641822-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-03-08 — — EP disclosed