Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437275 | 0.89 | SRD5A2 (0.74) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8433302 | 0.86 | SRD5A2 (0.70) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8070858 | 0.84 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMNPC1 | |
| SCHEMBL8083052 | 0.84 | MEN1 (0.57) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL6539987 | 0.82 | SRD5A2 (0.91) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8435714 | 0.81 | SRD5A2 (0.70) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8084620 | 0.79 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8070861 | 0.75 | SRD5A2 (0.74) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8070874 | 0.75 | SRD5A2 (0.57) | SRD5A2MEN1KMT2APKMALDH1A1 | |
| SCHEMBL8079904 | 0.74 | SRD5A2 (1.00) | SRD5A2MEN1KMT2APKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |