Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.50 |
| ▸ | RARB | P10826 | 9/20 | 0.50 |
| ▸ | RARG | P13631 | 9/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292935 | 0.83 | PDK2 (0.45) | RARARARBRARGPDK2 | |
| SCHEMBL6810766 | 0.80 | RARA (0.38) | RARARARBRARGPDK2MEN1 | |
| SCHEMBL6810768 | 0.79 | RARA (0.49) | RARARARBRARGEGFRPDK2 | |
| SCHEMBL6810772 | 0.79 | RARA (0.49) | RARARARBRARGEGFRPDK2 | |
| SCHEMBL8331635 | 0.79 | PDK2 (0.46) | RARARARBRARGPDK2 | |
| SCHEMBL15912453 | 0.77 | PLAU (0.52) | EGFRPLAUCA12CA1CA2 | |
| SCHEMBL17276192 | 0.77 | PDK2 (0.33) | RARARARBRARGPDK2 | |
| SCHEMBL8705923 | 0.77 | RARA (0.51) | RARARARBRARGEGFRPLAU | |
| SCHEMBL8437231 | 0.77 | RARB (0.66) | RARARARBRARGPLAUKMT2A | |
| SCHEMBL8664382 | 0.76 | RARB (0.44) | RARARARBRARGPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945561-A | ANTIINFLAMMATORY AGENT, RHEUMATIC DISORDERS, SKIN DISORDERS,ANTISCARRING AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |