Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 16/20 | 0.66 |
| ▸ | RARG | P13631 | 15/20 | 0.66 |
| ▸ | RARA | P10276 | 14/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709424 | 0.91 | RARB (0.63) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8709506 | 0.91 | RARB (0.80) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6907265 | 0.86 | RARB (0.64) | RARBRARGRARACYP11B1CYP11B2 | |
| SCHEMBL8438952 | 0.85 | RARB (0.56) | RARBRARGRARACYP11B1CYP11B2 | |
| SCHEMBL8709650 | 0.84 | CYP11B2 (0.58) | RARBRARGRARACYP11B1CYP11B2 | |
| SCHEMBL7807072 | 0.81 | RARA (0.64) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL7807061 | 0.81 | RARA (0.60) | RARBRARGRARACA1CA2 | |
| SCHEMBL7807064 | 0.81 | RARA (0.64) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8706490 | 0.81 | RARB (0.85) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8709537 | 0.80 | RARB (0.84) | RARBRARGRARARXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945561-A | ANTIINFLAMMATORY AGENT, RHEUMATIC DISORDERS, SKIN DISORDERS,ANTISCARRING AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |