Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432639 | 0.85 | MTNR1A (0.62) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8435177 | 0.83 | MTNR1A (0.69) | MTNR1ANQO2MTNR1B | |
| SCHEMBL7220756 | 0.83 | MTNR1A (0.69) | MTNR1ANQO2MTNR1B | |
| SCHEMBL5582711 | 0.81 | BAZ2B (0.52) | MTNR1A | |
| SCHEMBL7219800 | 0.81 | MTNR1A (0.73) | MTNR1ANQO2MTNR1B | |
| SCHEMBL5335761 | 0.81 | MTNR1A (1.00) | MTNR1ANQO2MTNR1B | |
| SCHEMBL8641270 | 0.80 | MTNR1A (0.53) | MTNR1AKDM4EMAPTMTNR1BMCHR1 | |
| SCHEMBL8433667 | 0.80 | MTNR1A (0.56) | MTNR1AKDM4EMAPTNQO2MTNR1B | |
| SCHEMBL8433448 | 0.80 | MTNR1A (0.43) | MTNR1ANQO2MTNR1B | |
| SCHEMBL7219370 | 0.79 | MTNR1A (0.70) | MTNR1ANQO2MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972964-A | FOR TREATMENT OF CERTAIN PSYCHIC AND NEUROLOGIC DISORDERS SUCH AS PSYCHOSIS, ANXIETY DISORDERS, PANIC DISORDER, OBSESSIVE COMPULSIVE DISORDER, DEPRESSION, IMPULSE CONTROL DISORDERS, ALCOHOL ABUSE, AGGRESSION | H. LUNDBECK A/S (DK) | 1999-10-26 | — | — | US | disclosed |
| US-5807889-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | H. LUNDBECK A/S (DK) | 1998-09-15 | — | — | US | disclosed |
| EP-0673360-B1 | AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES | LUNDBECK & CO AS H (DK) | 1998-08-26 | — | — | EP | disclosed |
| EP-0673360-A1 | AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES | H. LUNDBECK A/S (DK) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013620-A1 | AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES | H. LUNDBECK A/S (DK) | 1994-06-23 | — | — | WO | disclosed |