Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441984 | 0.73 | MEN1 (0.40) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL31267673 | 0.71 | LPAR3 (0.36) | LPAR3LPAR2ALDH1A1ADORA1CDK1 | |
| SCHEMBL31955606 | 0.67 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6515435 | 0.65 | MEN1 (0.45) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL6060419 | 0.65 | TDP1 (0.35) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL16581610 | 0.64 | ALDH1A1 (0.46) | LPAR3LPAR2ALDH1A1ADORA1LMNA | |
| SCHEMBL16581598 | 0.64 | ALDH1A1 (0.46) | LPAR3LPAR2ALDH1A1ADORA1LMNA | |
| SCHEMBL15365357 | 0.64 | ALDH1A1 (0.59) | LPAR3LPAR2ALDH1A1L3MBTL1 | |
| SCHEMBL10248293 | 0.64 | LMNA (0.36) | LMNAMEN1KMT2A | |
| SCHEMBL16581589 | 0.62 | ALDH1A1 (0.47) | LPAR3LPAR2ALDH1A1CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859017-A | PREVENTING OR TREATING ALLERGIES; INHIBITING INTRACELLULAR GENERATION OF PHOSPHATIDIC ACID AND DIACYLGLYCEROL | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1995026722-A1 | METHOD FOR INHIBITING MAST CELL AND BASOPHIL ACTIVATION | CELL THERAPEUTICS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |