Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386724 | 1.00 | AGTR1 (0.65) | AGTR1 | |
| SCHEMBL8954110 | 0.86 | AGTR1 (0.61) | AGTR1 | |
| SCHEMBL8954223 | 0.85 | AGTR1 (0.62) | AGTR1 | |
| SCHEMBL5547472 | 0.84 | AGTR1 (0.72) | AGTR1 | |
| SCHEMBL1258391 | 0.83 | AGTR1 (0.68) | AGTR1 | |
| SCHEMBL8957152 | 0.82 | AGTR1 (0.61) | AGTR1 | |
| SCHEMBL8954239 | 0.81 | AGTR1 (0.58) | AGTR1 | |
| SCHEMBL8438148 | 0.81 | AGTR1 (0.63) | AGTR1 | |
| SCHEMBL8954090 | 0.81 | AGTR1 (0.57) | AGTR1 | |
| SCHEMBL8954227 | 0.81 | AGTR1 (0.57) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |