Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383813 | 0.88 | ALDH1A1 (0.71) | MEP1BALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL6324179 | 0.84 | MEP1B (0.67) | MEP1BALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL7345656 | 0.82 | ALDH1A1 (0.62) | MEP1BALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL4173740 | 0.81 | MEP1B (0.67) | MEP1BALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL7244008 | 0.81 | MEP1B (0.59) | MEP1BALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL7410575 | 0.79 | MEP1B (0.91) | MEP1BCA1CA2MMP1MMP2 | |
| SCHEMBL5563528 | 0.76 | ALDH1A1 (0.86) | MEP1BALDH1A1PKMSMN1; SMN2CA1 | |
| SCHEMBL8448556 | 0.75 | MEP1B (0.52) | MEP1BALDH1A1PKMSMN1; SMN2KDM4E | |
| SCHEMBL7004195 | 0.74 | MEP1B (0.58) | MEP1BALDH1A1PKMSMN1; SMN2GAA | |
| SCHEMBL8446269 | 0.74 | MEP1B (0.58) | MEP1BALDH1A1PKMSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863949-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 1999-01-26 | — | — | US | disclosed |