Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 8/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.30 |
| ▸ | PPARA | Q07869 | 3/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430536 | 0.93 | LTB4R (0.42) | LTB4R | |
| SCHEMBL8432882 | 0.90 | LTB4R (0.57) | LTB4RTERTMAPTKDM4EALDH1A1 | |
| SCHEMBL8430695 | 0.88 | LTB4R (0.51) | LTB4RTERTMAPT | |
| SCHEMBL8434050 | 0.86 | LTB4R (0.51) | LTB4RTERTMAPT | |
| SCHEMBL8434502 | 0.84 | LTB4R (0.53) | LTB4R | |
| SCHEMBL8430558 | 0.82 | LTB4R (0.55) | LTB4RTERTCHRM5CHRM1ALDH1A1 | |
| SCHEMBL8432444 | 0.82 | LTB4R (0.54) | LTB4RTERTPPARG | |
| SCHEMBL8434253 | 0.79 | LTB4R (0.58) | LTB4RTERTMAPT | |
| SCHEMBL8434516 | 0.78 | LTB4R (0.50) | LTB4RTERT | |
| SCHEMBL8434140 | 0.77 | LTB4R (0.47) | LTB4RTERTMAPTPPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929096-A | TREATING DISEASES ATTRIBUTING THEIR ORIGIN OR AFFECT TO LEUKOTRIENES, ANTIALLERGENS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |