Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.30 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430541 | 0.94 | LTB4R (0.42) | LTB4RPTGER1 | |
| SCHEMBL8432889 | 0.91 | LTB4R (0.57) | LTB4RPTGER1MAPTTERTKDM4E | |
| SCHEMBL8430702 | 0.89 | LTB4R (0.51) | LTB4RPTGER1MAPTTERT | |
| SCHEMBL8434056 | 0.87 | LTB4R (0.51) | LTB4RPTGER1MAPT | |
| SCHEMBL8434513 | 0.85 | LTB4R (0.53) | LTB4RPTGER1 | |
| SCHEMBL8430563 | 0.83 | LTB4R (0.55) | LTB4RPTGER1TERTKDM4E | |
| SCHEMBL8432449 | 0.83 | LTB4R (0.54) | LTB4RPTGER1TERTALOX5PPARG | |
| SCHEMBL8430495 | 0.81 | LTB4R (0.55) | LTB4RPTGER1CNR2MAPTTERT | |
| SCHEMBL8434257 | 0.80 | LTB4R (0.58) | LTB4RALDH1A1 | |
| SCHEMBL8434525 | 0.79 | LTB4R (0.50) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929096-A | TREATING DISEASES ATTRIBUTING THEIR ORIGIN OR AFFECT TO LEUKOTRIENES, ANTIALLERGENS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |